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院士簡歷


生命科學組


院士相片
Phillip A. Sharp
當選名譽院士年 2008
Koch Institute for Integrative Cancer Research
Massachusetts Institute of Technology, Rm. 76-461A
77 Massachusetts Avenue
Cambridge, MA 02139-4307, U.S.A.
Tel: (617) 253-6421 / Fax: (617) 253-3867
院士email

現職
  • Institute Professor (highest academic rank), MIT
學歷
  • B.A., Chemistry & Mathematics, Union College, Barbourville, KY (1966)
  • Ph.D., Chemistry, University of Illinois, Urbana (1969)
經歷
  • POSITIONS
  • Research Assistant, Department of Chemistry, University of Illinois (1966-1669)
  • Postdoctoral Fellow, California Institute of Technology (1969-1971)
  • Postdoctoral Fellow, Cold Spring Harbor Laboratory (1971-1972)
  • Senior Research Investigator, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (1972-1974)
  • Associate Professor, Center for Cancer Research and Department of Biology, MIT (1974-1979)
  • Professor, Center for Cancer Research and Department of Biology, MIT (1979-1999)
  • Associate Director, Center for Cancer Research, MIT (1982-1985)
  • Director, Center for Cancer Research, MIT (1985-1991)
  • Salvador E. Luria Professor of Biology, MIT (1991-1999)
  • Head, Department of Biology, MIT (1991-1999)
  • Institute Professor (highest academic rank), MIT (1999-date)
  • Director, The McGovern Institute (2000-2004)
  • SERVICE
  • Member of the advisory committee, MIT Institute for Medical Engineering and Science (IMES), (2012–current)
  • Member of the Board of the Broad Institute, (2009–current)
  • Chair of the Scientific Advisory Committee, SU2C Project, AACR, (2008–current)
  • Member of the Board of the Whitehead Institute, (2005-current)
  • President and Chairman of the American Association for the advancement of Science, (2013–2015)
  • Member of the HHMI MAB and Review Committee, (2011–2015)
  • Co-Chair of MIT’s Production in an Innovation Economy (PIE) Commission, (2010–2013)
  • Chair of the Scientific Review Council of the Cancer Prevention and Research Institute of Texas (CPRIT)
  • Ad Hoc Member of the Committee to Consider the Future of HST at MIT (2010)
  • Member of the World Economic Forum (WEF) Technology Pioneers PPOSITIONS
  • Research Assistant, Department of Chemistry, University of Illinois (1966-1669)
  • Postdoctoral Fellow, California Institute of Technology (1969-1971)
  • Postdoctoral Fellow, Cold Spring Harbor Laboratory (1971-1972)
  • Senior Research Investigator, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York (1972-1974)
  • Associate Professor, Center for Cancer Research and Department of Biology, MIT (1974-1979)
  • Professor, Center for Cancer Research and Department of Biology, MIT (1979-1999)
  • Associate Director, Center for Cancer Research, MIT (1982-1985)
  • Director, Center for Cancer Research, MIT (1985-1991)
  • Salvador E. Luria Professor of Biology, MIT (1991-1999)
  • Head, Department of Biology, MIT (1991-1999)
  • Institute Professor (highest academic rank), MIT (1999-date)
  • Director, The McGovern Institute (2000-2004)
  • SERVICE
  • Member of the advisory committee, MIT Institute for Medical Engineering and Science (IMES), (2012–current)
  • Member of the Board of the Broad Institute, (2009–current)
  • Chair of the Scientific Advisory Committee, SU2C Project, AACR, (2008–current)
  • Member of the Board of the Whitehead Institute, (2005-current)
  • President and Chairman of the American Association for the advancement of Science, (2013–2015)
  • Member of the HHMI MAB and Review Committee, (2011–2015)
  • Co-Chair of MIT’s Production in an Innovation Economy (PIE) Commission, (2010–2013)
  • Chair of the Scientific Review Council of the Cancer Prevention and Research Institute of Texas (CPRIT)
  • Ad Hoc Member of the Committee to Consider the Future of HST at MIT (2010)
  • Member of the World Economic Forum (WEF) Technology Pioneers Program 2010 Selection Committee in the Area of iotechnology/Health (2010)
  • Ad hoc member of the NIH/MIT Convergence White Paper on "The Third Revolution: Convergence of the Life Sciences, Physical Sciences and Engineering (2010)
  • Co-chair, NRC Committee on A New Biology for the 21st Century: Ensuring the United States Leads the Coming Biology Revolution, National Academy of Sciences (2008-2010)
  • Member of the Board of FDA’s Reagan-Udall Foundation (2008-2012)
  • Elected member of the MIT Museum Advisory Board (2005- current)
  • Member of the National Academies Committee on Scientific Communication and National Security(CSCANS) (2005-2009)
  • Member, Lasker Jury of the Lasker Foundation (2007-2015)
  • Member of the Scientific Advisory Board of the Ontario Institute for Cancer Research (OICR) (2006-2009)
  • Elected Member of the Board of Directors of the Whitehead Institute, (2005-current)
  • Member of the Gairdner Foundation Awards Committee (2004- current)
  • Elected Member of the Corporation of Partners HealthCare Systems, Inc. (2003-current)
  • Member of the Board of Trustees of the Massachusetts General Hospital (2002-2011)
  • Honorary Member of the Board of Trustees, MGH (2011- current)
  • Member and Chair, Committee on Research and Education, Partners HealthCare Systems Inc. (2003-2012)
  • Member of the Nominating Committee, Partners HealthCare Systems Inc. (2005- current)
  • Member of the Board of Scientific Governors of the Scripps Research Institute (1999- current)
  • Member of the Science Advisory Committee for the Sandler Basic Science Program, UCSF (1999-2007)
  • Member of the Scientific Committee of the Ludwig Institute for Cancer Research (1998-2008)
  • Member of the Scientific Board of Advisors, The Van Andel Institute (1996- current)
  • Chairman of the Scientific and Medical Advisory Board of the Huntsman Cancer Foundation (1995-2001)
  • Trustee and Member of the Alfred P. Sloan Foundation (1995-2004)
  • Chairman of the General Motors Cancer Research Foundation Awards Assembly (1994-2006)
  • Member of the Faculty of the Harvard-MIT Division of Health Sciences and Technology
  • Member of the Review Committee, The Medical Foundation (Health Resources in Action) (1982–2005), and its Chairman (1988-2005)
  • Member of the Advisory Council of the Molecular Biology Department, Princeton University (1987–2003)
  • GOVERNMENT SERVICE
  • Member of the NCI Translational Science Program (2010)
  • Co-Chair of the National Cancer Advisory Board (NCAB) Working Group of the National Cancer Institute (NCI), NIH ( 2010)
  • Committee on Science Engineering and Public Policy (COSEPUP), Assuring the Integrity of Research Data in an Era of E-Science, National Academy of Sciences (2007)
  • NHGRI Large-Scale Sequencing Program, committee member (2002–2012)
  • NSABB committee member (2005–2009)
  • Mammalian Gene Collection ESC committee member (2002–2012)
  • Member of the National Cancer Advisory Board (NCAB), NCI (1996-2000)
  • Chairman of the National Cancer Advisory Board (NCAB), NCI (2000-2002)
  • Member of the NCI Advisory Committee to the Director (2000-2001)
  • Member of the President’s Committee of Advisors on Science and Technology (PCAST) (1994-1997)
  • Member, Committee on Science, Engineering, and Public Policy (COSEPUP) (1992-1995)
  • INDUSTRY
  • Member of the Board of Directors, Vir Biotechnology, Inc (2017–current)
  • Member of the Scientific Advisory Board and Board of Directors of Syros Pharmaceuticals (2013–current)
  • Member of the Scientific Advisory Board of Sirtris Pharmaceuticals (2003–2010)
  • Member of the Scientific Advisory Board of Fidelity Biosciences Group (2004–current)
  • Member of the Board of Advisors, Polaris Venture Partners (2002–current)
  • Member of the Advisory Board of Verastem (2010–current)
  • Advisor and Investor in the Longwood Fund (2010–current)
  • Co-founder of Biogen, Inc., 1978, Chairman of the Scientific Board (to 2002) and member of the Board of Directors (to 2009)
  • Co-founder of Alnylam Pharmaceuticals (2002), Chairman of the Scientific Board and member of the Board of Directors (2002–current)
  • PROFESSIONAL SOCIETIES
  • The National Academy of Sciences
  • The Institute of Medicine
  • The American Association for the Advancement of Science
  • The American Society of Biological Chemists
  • The American Association for Cancer Research
  • The American Chemical Society
  • The American Society for Microbiology
  • The American Academy of Arts and Sciences
  • The American Society for Biochemistry and Molecular Biology
  • The American Philosophical Society
  • EDITORIAL BOARDS
  • J. Virol. (to 1985), Mol. Cell. Biol. (to 1985), Virology (to 1986), Cell (to 1995), Genes & Development (1987–current),
  • RNA (1995–current)
專長
  • Molecular Biology, Biochemistry
曾獲得之學術榮譽
  • 1974-1979 Recipient of an American Cancer Society Career Development Award
  • 1980 The National Academy of Sciences’ U.S. Steel Foundation Award in Molecular Biology
  • 1980 The Eli Lilly Award in Biological Chemistry
  • 1983 Elected to the American Academy of Arts and Sciences
  • 1983 Elected to the National Academy of Sciences
  • 1985 The Harvey Society Lecture
  • 1985 The Howard Ricketts Award, The University of Chicago
  • 1986-1987 Class of ‘41 Professorship (Chair), MIT
  • 1986 The General Motors Research Foundation Alfred P. Sloan, Jr. Prize for Cancer Research
  • 1986 The Gairdner Foundation International Award, Canada
  • 1986 The New York Academy of Sciences Award in Biological and Medical Sciences
  • 1987-1990 Elected Councilor of the National Academy of Sciences
  • 1987 Elected Fellow of the American Association for the Advancement of Science
  • 1987-1992 The John D. MacArthur Professorship (Chair), MIT
  • 1988 Louisa Gross Horwitz Prize, Columbia University
  • 1988 The Albert Lasker Basic Medical Research Award
  • 1990 The Dickson Prize, University of Pittsburgh
  • 1991 Elected Member of the Institute of Medicine of the National Academy of Sciences
  • 1991 Elected Member of the American Philosophical Society
  • 1991 Honorary Degree of Doctor of Humane Letters from Union College, Barbourville, KY
  • 1992-1999 The Inaugural Salvador E. Luria Professorship (Chair), MIT
  • 1993 The Mendel Medal Award from Villanova University, Villanova, PA
  • 1993 The James R. Killian, Jr., Faculty Achievement Award, MIT
  • 1993 Elected Fellow of the American Academy of Microbiology
  • 1993 The Nobel Prize in Physiology or Medicine
  • 1994 Honorary Doctor of Science Degree, University of Kentucky
  • 1995 Honorary Doctor of Science Degree, Bowdoin College, Brunswick, ME
  • 1996 Honorary Doctor of Science, University of Tel Aviv
  • 1996 Honorary Doctor of Science, Albright College, Reading, PA
  • 1998 Honorary Doctor of Science, University of Glasgow, Scotland
  • 1999 Honorary Doctor of Science, Thomas More College, KY
  • 1999 The Benjamin Franklin Medal of the American Philosophical Society
  • 1999 Institute Professor, MIT
  • 1999 Honorary Doctor of Medicine, Uppsala University, Sweden
  • 1999 Doctor Honoris Causa, University of Buenos Aires, Argentina
  • 2001 The Walker Prize from the Museum of Science, Boston, MA
  • 2001 The Norman Davidson Lecture, California Institute of Technology
  • 2001 Honorary Doctorate, Northern Kentucky University
  • 2002 Lifetime Honorary Member of the Kentucky Academy of Sciences
  • 2002 Elected Honorary Fellow of the Royal Society of Edinburgh, Scotland
  • 2002 The Storer Life Sciences Lectures, University of California, Davis
  • 2002 The Fourth Annual Biotechnology Heritage Award from the Biotechnology Industry Organization (BIO) and the Chemical Heritage Foundation (CHF)
  • 2003 Received the University of Illinois Alumni Achievement Award
  • 2003 Novartis Drew Award in Biomedical Research
  • 2004 Honorary Member, The National Academy of Sciences-Republic of Korea
  • 2005 The University College Dublin Ulysses Inaugural Lecturer, Dublin, Ireland
  • 2005 KT Wang Foundation Bioorganic Chemistry Lecturer, The National Taiwan University and Academia Sinica, Taiwan
  • 2005 Third Princess Chulabhorn Distinguished Lecturer, Chulabhorn Research Institute, Bangkok, Thailand
  • 2005 The 2004 National Medal of Science
  • 2006 The AACR Irving Weinstein Distinguished Lectureship Award
  • 2006 Honorary Doctorate, Rippon College, Ripon, Wisconsin
  • 2006 The Inaugural Double Helix Medal for Scientific Research from Cold Spring Harbor Laboratory
  • 2007 The Winthrop-Sears Award from the Chemists’ Club of New York
  • 2007 The Karl Friedrich Bonhoeffer Lecture, Max Planck Institute, Göttigen, Germany
  • 2008 Honorary Doctorate, Bates College, Maine
  • 2008 Honorary Doctorate, Eberly College of Science (Penn State), State College, Pennsylvania
  • 2008 Honorary Academician of Academia Sinica, Republic of China
  • 2010 American Society for Biochemistry and Molecular Biology Herbert Tabor/Journal of Biological Chemistry Lectureship
  • 2010 AACR Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research
  • 2011 Honorary Degree, Doctor of Science, University of Minnesota
  • 2011 Elected Foreign Fellow of the Royal Society, UK
  • 2012-2013 President-Elect, American Association for the Advancement of Science (AAAS)
  • 2012 Han-Mo Koo Memorial Lecture, Van Andel Research Institute, Grand Rapids, MI
  • 2012 The Christian A. Herter Lecture, New York University School of Medicine
  • 2012 Honorary degree of Doctor of Science, McGill University, Montreal, QC, Canada
  • 2013 Award of Excellence from the Hope Funds for Cancer Research
  • 2013-2014 President, American Association for the Advancement of Sciences (AAAS)
  • 2013 Selected a Vallee Visiting Professor
  • 2013 The Lifetime Achievement in Science Award from the RNA Society
  • 2013 Elected Fellow of the AACR Academy
  • 2014 The SU2C Phillip A. Sharp Innovation in Collaboration Awards to foster collaboration among members of the SU2C scientific community that would enhance the SU2C mission to accelerate the development of new cancer treatments
  • 2014 Honorary degree of Doctor of Science, University of Southern California, Los Angeles, CA
  • 2014 Honorary degree of Doctor of Science, University of Illinois at Urbana-Champaign
  • 2014-2015 Chair of the AAAS Board
  • 2015 Othmer Gold Medal, Chemical Heritage Foundation
  • 2016 Honorary degree of Doctor of Science, The Scripps Research Institute, La Jolla, CA
  • 2017 Raymond and Beverly Sackler Award for Sustained National Leadership, Research America, Washington, DC
  • 2017 Shattuck Lecture, Massachusetts Medical Society, Boston, MA