1980-1981 Research technician, Food Industry Research and Development Institute
1987-1989 Ohio State University, Postdoc, Molecular Biology
1990-1992 Baylor College of Medicine, Postdoc, Human Genetics
1993-1995 Scientist, Millennium Pharmaceuticals, Inc.
1995-1997 Senior Scientist, Darwin Molecular Corp.
1997-2002 Associate Professor, University of Utah
2002-2006 Associate Professor, Department of Neurology, University of California, San Francisco
2006- Professor, Department of Neurology, University of California, San Francisco
2014- Visiting Professor, Graduate Institute of Brain and Mind Sciences, National Taiwan University College of Medicine